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The thicker outer leaflet of theurothelial plaque contains a crystalline array of hexagonallyarranged 16-nm protein particles composed ofa family offivetransmembrane proteins called uroplakins (UPIa, UPIb,UPII, UPIIIa, and UPIIIb; Fig. Sulfur It is the oldest scabicide and weak pediculo-cide, antiseptic, fungicide and keratolytic

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